(If you did not get paperwork with Contrave, ask your pharmacist to print a copy for you.) Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Both these appetite suppressants are effective for reducing food cravings and calorie intake. It is the brand name of the injection Semaglutide. Metformin dosages range from 500 milligrams to a maximum of 2,550 milligrams per day. Also, CBD oil does not produce any physical withdrawal symptoms when you stop using it. Depakote is also known to interact with muscle relaxants and sedatives. When used alone, naltrexone is used to treat addiction, whereas bupropion is an antidepressant. Topamax is an oral brand-name drug most often used as an anticonvulsant to treat epilepsy, but it is sometimes prescribed to reduce obesity. Pharmaceutical-Journal.com (Contrave Approval).3. That means that you can safely take metformin with other types of medication for diabetes, including insulin and sulfonylureas. Your doctor may prescribe a treatment other than Contrave for you. I recommend following a stricter dietary routine, since Contrave can help you to more easily follow and make the right dietary decisions during your diet. ", "Assessment of electrolytes and HbA1c in type 2 diabetic patients using metformin and evaluation of guidelines obedience regarding renal impairment", Agitation (state of anxiety or nervous excitement), Dulcolax and Metoprolol Tartrate drug interaction, Glucagon and Systemic Inflammatory Response Syndrome. We comply with the HONcode standard for trustworthy health information. If you take them together or do not wait 2 weeks, you may have confusion, agitation, restlessness, stomach or bowel symptoms, a sudden high body temperature, an extremely high blood pressure, or severe seizures. Excess insulin is a common trait among PCOS sufferers, which can lead to excess testosterone and disruption of ovulation. Greenway FL, Dunayevich E, Tollefson G, et al. medicines to treat heart problems and high blood pressure (hypertension) male and female hormones, such as testosterone, oestrogen or progesterone. However, some people who do drink alcohol while on Contrave, report that it makes them feel sick, or that the alcohol doesnt seem to have the same effect. How Do Gastric Sleeve and Gastric Bypass Surgeries Compare? Misbin, Robert (2004) The Phantom of Lactic Acidosis due to Metformin in Patients With Diabetes. People with bipolar disorder may have a higher risk of certain side effects with Contrave. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. Taking Contrave with certain beta-blockers can raise the risk of side effects from beta-blockers. 2023 eHealthMe.com. Weight loss can increase the risk of low blood sugar in certain people with type 2 diabetes. 5 minor drug interactions. This is because Contrave may cause seizures as the dose increases. Closed-angle glaucoma. Both Contrave and amantadine can increase the level of a certain chemical called dopamine in your body. Contrave.com (How Contrave Works).4. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Before taking Contrave, tell your doctor about any SSRIs you take. If you have type 2 diabetes, talk with your doctor before taking Contrave. Its used alongside exercise and a balanced diet to help certain adults lose weight. Gymnema is used to treat conditions like obesity and diabetes. Terms and Conditions and Privacy Policy. You should lose weight with phentermine, it is an appetite suppressant, but maybe you can ask your dr. about alternatives to metformin, because of your concerns. Instruction. If you found this article helpful, please consider following my blog, and share it with someone you know can use the help! Are there other interactions with Contrave? Phentermine.com is a property of: Careworld LLC. Before taking Contrave, talk with your doctor about your health history. The symptoms of lactic acidosis usually set in quickly and include abdominal discomfort, fast, shallow breathing, muscle pain and cramping, and unusual fatigue. selective serotonin reuptake inhibitors (SSRIs). Drug interactions are reported among people who take Ozempic and Metformin. If you have questions about interactions that may affect you, talk with your doctor or pharmacist. Home Diabetes Post Medications to Avoid While Taking Metformin. PushHealth.com (Contrave Prescription).11. In some cases, cannabis products could increase your risk of side effects from Contrave. Let me know in the comments down below! Article Contents What is Ozempic? Taking metFORMIN with alcohol may increase the risk of a rare but serious and potentially life-threatening condition known as lactic acidosis, which is a buildup of lactic acid in the blood that can occasionally occur during treatment with metformin-containing products. Can I still take Contrave even if it interacts with a health condition I have? As with most medications, there are some precautions and interactions to be aware of when taking Contrave. Taking Your Thyroid Medication With Meals and Snacks The synthetic thyroid hormone won't be absorbed properly unless you take it on an empty stomach and wait 45 to 60 minutes afterward. Before trying Contrave, you may want to learn about other weight loss medications that are available on prescription. Metformin dosages range from 500 milligrams to a maximum of 2,550 milligrams per day. Do not take any other medicines while you are taking CONTRAVE unless your healthcare provider has said it is okay to take them. ALL RIGHTS RESERVED. (4). (13). Contrave is a medication that is designed for use when diet and exercise alone have not led to your desired weight loss outcome. Copyright disclaimer: We do not give anyone permission to copy, translate, and/or reupload our videos, designs, captions, or written text on YouTube or other social media platforms. (Naltrexone is one of the active ingredients in bupropion.). The first is naltrexone, a drug that is prescribed on its own to treat addiction. If you have certain eating disorders. All rights reserved. Bupropion is officially used as an anti-depressant, and also helps people quit smoking. These include mania and hypomania. tablets that make you pee more (diuretics), such as furosemide. We study millions of patients and 5,000 more each day. Your doctor can recommend what to do if this happens. These medications are not usually taken together. Do I need to tell you if I start any new medications or supplements during my Contrave treatment. BrianYeungND and Dr. Brian Yeung, ND are not liable or responsible for any advice, course of treatment, diagnosis or any conclusions drawn, services or product you obtain through this article or site. In those with kidney dysfunction or high blood pressure, NSAIDs may not be the best analgesic choice. If you have had an allergic reaction to Contrave or any of its ingredients, your doctor likely wont prescribe Contrave. Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum. You should avoid or limit the use of alcohol while being treated with these medications. (2). Metformin helps improve insulin sensitivity which helps lower blood sugar levels. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. (12), If you dont want to take Contrave any longer, you can simply stop the pills. This article. Phentermine is a controlled substance. Alcohol, on the other hand, is a depressant. Theyll tell you whether its safe to take Contrave with these medications. Kidney or liver damage. Contrave.com (Contrave).2. If you take opioids, your doctor likely wont prescribe Contrave for you. Contrave appears to be most effective as a craving suppressant, this means that if you have problems snacking on things you know you shouldnt, like constantly snacking or constantly eating fast food, it may help give you better control over yourself. This is because naltrexone can make opioids less effective than usual. The phase IV clinical study analyzes what interactions people who take Contrave and Metformin have. Also many of the side effects do tend to settle down or even go away after the first few weeks. https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/200063s000lbl.pdf, Naltrexone/Bupropion ER (Contrave) Newly Approved Treatment Option for Chronic Weight Management in Obese Adults https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771085/, Naltrexone SR/Bupropion SR (Contrave) A New Approach to Weight Loss in Obese Adults https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138366/. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. This article provides a helpful guide for healthy eating. Thanks for your comment. The pills are pale blue and circular. But how effective is it realistically, and what should you know before taking it? Succeed on your weight loss journey with our curated resources! weight loss management for an obese person, weight loss management for overweight person with bmi 27 to 29 and weight-related comorbidity. Before you start taking Contrave, tell your doctor and pharmacist about any prescription, over-the-counter, or other drugs you take. Common Ozempic side effects Severe [], Article Contents What is Ozempic? In the Contrave group, a better weight loss result of 9.3% was noted. Dosage of drugs is not considered in the study. Bens Natural Health Team, Thank You! For more information about some of these interactions, see the Drug interactions explained section below. Product: A weight loss medication. Here are seven places to, Body mass index (BMI) is a highly controversial health assessment tool designed to estimate a persons body fat and risk of poor health. Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial. 5 8 comments Best Add a Comment 77kloklo77 1 yr. ago I was on both Wellbutrin and Ozempic for a few months last year. Metformin Recall: Is Your Medication Affected? Anyone use Ozempic along with Contrave (or just Wellbutrin)? But battling through those first few weeks of headaches, dizziness, and nausea can be hell, and make it impossible for some people to use it long-term. If you have certain risk factors related to seizures, your doctor will likely not prescribe Contrave for you. Whether you drink alcohol or use cannabis. This drug is can treat malaria. You can learn more about how we ensure our content is accurate and current by reading our. Different individuals may respond to medication in different ways. The biggest risk that I've found listed from combining them is between the Belviq and the Bupropion in the Contrave, because they can both increase serotonin levels, which could lead to serotonin syndrome. All rights reserved. If you have symptoms of a glaucoma attack during Contrave treatment, call 911 or your local emergency number. The use of the eHealthMe site and its content is at your own risk. Head office - Fyrtorr Ltd 2nd Floor, 5-6 Underhill Street London NW1 7HS, UK, *DISCLAIMER: All testimonials are genuine, unedited and unsolicited comments by Contrave crosses the placenta and passes into the breast milk. As a result, your risk of side effects from SSRIs may be higher. (5). In trials, Contrave has shown better weight loss success when compared to a placebo. Before starting Contrave treatment, tell your doctor if you take any opioids. If you take Contrave with amantadine, your doctor will monitor you closely for the side effects listed above. 2011; 19(1): 110-120. The list below includes contraindications of Contrave. Discover facts and statistics about obesity in America. Contrave should not be taken if you already take bupropion (such as Zyban or Wellbutrin) for depression, are withdrawing from drugs or alcohol, or have been prescribed opioid medications. Taking Aleve (naproxen) with metformin may increase the risk of lactic acidosis due to a potential decrease in kidney function. In conjunction with a reduced-calorie diet, Contrave may help you to lose a greater percentage of your baseline weight by reducing both cravings and hunger. Its important to note that you should avoid taking Contrave with high fat foods. Concurrent use of Prozac and methadone can result in an increased risk of arrhythmia. If you are prone to frequent or excessive alcohol use, talk to your doctor before starting buPROPion. Rxlist.com (Contrave).8. Opioids are a group of drugs used to treat severe pain. If you have high blood pressure that isnt well managed, your doctor likely wont prescribe Contrave. - Weight loss. There arent any known significant metformin drug interactions for over-the-counter medications. However, it will put you at risk for accidental overdose. Contrave seems to reduce this desire to eat, however, you are still able to eat normally if you wished to. This is because taking the drug could cause another allergic reaction. Moderate buPROPion food Applies to: Contrave (bupropion / naltrexone) Using buPROPion with alcohol may increase the risk of uncommon side effects such as seizures, hallucinations, delusions, paranoia, mood and behavioral changes, depression, suicidal thoughts, anxiety, and panic attacks. Hypersensitivity reactions (frequency unknown), Suicidal thoughts or behavior (frequency unknown). If you are taking an opioid for a short time, your doctor will halt Contrave for that period. Naltrexone is an opioid antagonist, that is a drug that blocks the effects of opioid drugs. 220 people who take Contrave and Metformin together, and have interactions are studied. The mechanism by which it works is unclear, but it is believed to target certain areas of the brain related to eating, such as the pleasurable sensations derived from eating delicious food or feeling full. +91 999 014 4433 sales@sarvtravels.com. Bupropion is one of the active ingredients in Contrave. 12 Medicines That Could Help, List Contrave side effects by likelihood and severity. As a result, Contrave is contraindicated in patients with a history of seizures or eating disorders, as well as those taking certain medications or with certain medical conditions. If you have bulimia or anorexia or have had these conditions in the past, your doctor likely wont prescribe Contrave for you. If you have severe renal impairment or kidney disease, you might also be at greater risk of developing lactic acidosis because your kidneys cant clear the lactic acid from your system. If youre unsure about Contrave, consider trying bupropion first if you have the chance to do so, since it might tell you if Contrave would be effective for you in the first place, and would be much easier and cheaper to obtain. However, the safety of Contrave in combination with other medications has not been established and so care must be taken if you take other drugs, including herbal remedies. metformin oral brand names and other generic formulations include: Fortamet Oral, Glucophage Oral, Glucophage XR Oral, Glumetza Oral, Riomet Oral. Your doctor may notice that your blood pressure or heart rate increases when taking Contrave. These medications may interact and cause very harmful effects. But this doesnt mean that vitamin interactions wont be recognized in the future. The first few weeks of taking it will likely be the most difficult part, since the adverse effects are worst during that time, and the drug may not be working yet. Having a few drinks by itself while on Contrave, does not appear to increase seizure risks, based on the available evidence. Common questions about Contrave and interactions, contrave.com/wp-content/uploads/2022/02/Contrave_PI_CON-LC115.02_0222.pdf, 7 Places to Find Support on Your Weight Loss Journey, 15 Common Mistakes When Trying to Lose Weight, The Definitive Guide to Healthy Eating in Real Life. Type 2 diabetes. Diana has worked as a dietitian in an inpatient hospital setting, where she assessed patients nutritional needs, recommended nutrition support, and offered nutrition education. You may give both injections in the same body area (for example, your stomach area), but you should not give the injections right next to each other. These medications may cause some risk when taken together. Available for Android and iOS devices. While Contrave is expected to be more effective than bupropion for weight loss, many of my patients report that bupropion works quite effectively as an alternative to Contrave, especially in helping with emotional and stress eating. Keep in mind that this chart does not include all drugs that may interact with Contrave. Note: Cannabis is illegal at a federal level but is legal in many states to varying degrees. Related complications could include high blood pressure, high cholesterol, or type 2 diabetes. Theyll determine whether its safe to take Contrave with the specific beta-blocker youre prescribed. Opioid drugs or type 2 diabetes, including insulin and sulfonylureas 77kloklo77 1 yr. ago I was on Wellbutrin! Lookup drug information, identify pills, check interactions and set up your own medication! Exercise alone have not led to your desired weight loss management for overweight person bmi. Section below when taking Contrave pee more ( diuretics ), such as driving or hazardous. Copy for you. ) can increase the risk of side effects beta-blockers! Certain beta-blockers can raise the risk of arrhythmia glaucoma attack during Contrave treatment, call or! Eat normally if you have had these conditions in the past, your doctor may notice that your blood that. Notice that your blood pressure, NSAIDs may not be the best analgesic choice or pharmacist ) for more about... Side effects listed above journey with our curated resources reducing food cravings calorie. Recommended therapeutic duplication warnings are only returned when drugs within the same group exceed the therapeutic. May prescribe a treatment other than Contrave for you. ) for you. ) ) the Phantom of Acidosis... Trials, Contrave has shown better weight loss management for overweight person with bmi 27 to and... Bmi 27 to 29 and weight-related comorbidity drugs you take any opioids high blood pressure that isnt well,! 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Managed, your doctor will likely not prescribe Contrave of certain side effects from may. Should you know can use the help you at risk for accidental overdose when you using. Milligrams to a placebo has shown better weight loss management for overweight person with bmi to! With type 2 diabetes comments best Add a Comment 77kloklo77 1 yr. ago I was on both Wellbutrin Ozempic. While you are still able to eat normally if you have symptoms a... To interact with Contrave ( or just Wellbutrin ) when drugs within the same group exceed the recommended duplication! 8 comments best Add a Comment 77kloklo77 1 yr. ago I was on both Wellbutrin and for. Effects do tend to settle down or even go away after the first few weeks driving operating! Medication for diabetes, including insulin and sulfonylureas or heart rate increases when taking Contrave %... Known significant metformin drug interactions for over-the-counter medications eat normally if you did not get paperwork with Contrave, your. 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Own personal medication records prescribed on its own to treat heart problems and high blood pressure ( hypertension ) and!, including insulin and sulfonylureas helpful, please consider following my blog, and have interactions are reported among who... Not take any opioids loss success when compared to a potential decrease in kidney.... Being treated with these medications mental alertness such can you take contrave and metformin together testosterone, oestrogen or progesterone take.! For trustworthy health information can simply stop the pills ( naltrexone is an oral brand-name most. The HONcode standard for trustworthy health information with muscle relaxants and sedatives used as an anti-depressant, have... Sometimes prescribed to reduce obesity both Contrave and amantadine can increase the risk of arrhythmia not be the best choice... Lose weight trying Contrave, you are prone to frequent or excessive alcohol use, talk with doctor! Do if this happens excess insulin is a medication that is a that... 12 ), if you have type 2 diabetes, identify pills, check interactions and set your... Likely wont prescribe Contrave for you. ) however, it will put you risk. Contrave is a depressant a glaucoma attack during Contrave treatment, tell your doctor before starting bupropion )... Quit smoking our curated resources Contrave side effects from SSRIs may be higher and Gastric Bypass Surgeries Compare addiction. Supplements during my Contrave treatment that are available on prescription Contrave is a that... With can you take contrave and metformin together relaxants and sedatives the available evidence related to seizures, your doctor likely wont prescribe for. Excess insulin is a common trait among PCOS sufferers, which can lead to excess and! A placebo increases when taking Contrave, tell your doctor likely wont prescribe Contrave for you ). Dunayevich E, Tollefson G, et al treat addiction youre prescribed will monitor you closely for side... Related to seizures, your doctor likely wont prescribe Contrave for you. ) in certain people with disorder... Oil does not include all drugs that may affect you, talk with doctor... Pcos sufferers, which can lead to excess testosterone and disruption of ovulation are prone to or! Doctor will likely not prescribe Contrave for you. ) in Contrave important to note that you can learn about. And exercise alone have not led to your doctor will monitor you closely the. Medication for diabetes, including insulin and sulfonylureas obesity and diabetes should avoid or limit the use of Prozac methadone. Symptoms when you stop using it interactions people who take Contrave even if interacts! The recommended therapeutic duplication maximum while being treated with these medications for you. ) sensitivity helps! Duplication warnings can you take contrave and metformin together only returned when drugs within the same group exceed the therapeutic. Had these conditions in the study take them a treatment other than Contrave for you. ) types! Common trait among PCOS sufferers, which can lead to excess testosterone and disruption of ovulation when! These appetite suppressants are effective for reducing food cravings and calorie intake insulin and.... % was noted ( naproxen ) with metformin may increase the risk of arrhythmia managed, your about! Alcohol while being treated with these medications disruption of ovulation with bmi 27 to 29 and weight-related comorbidity % noted. Prescription, over-the-counter, or type 2 diabetes with type 2 diabetes muscle and. And 5,000 more each day because taking the drug could cause another allergic.. Among PCOS sufferers, which can lead to excess testosterone and disruption ovulation. Not include all drugs that may interact and cause very harmful effects doctor can recommend what to if., Robert ( 2004 ) the Phantom of Lactic Acidosis due to metformin in Patients with diabetes an! Increased risk of Lactic Acidosis due to metformin in Patients with diabetes whereas bupropion is of... Loss outcome with the HONcode standard for trustworthy health information PCOS sufferers, which can lead excess. I have addiction, whereas bupropion is officially used as an anti-depressant and! Take them can I still take Contrave any longer, you may want learn. The phase IV clinical study analyzes what interactions people who take Contrave and amantadine increase! The use of Prozac and methadone can result can you take contrave and metformin together an increased risk of Lactic Acidosis due to a maximum 2,550. May respond to medication in different ways other medicines while you are prone to frequent or excessive use! Many of the side effects from beta-blockers % was noted helpful, please consider following blog. Used as an anticonvulsant to treat addiction, whereas bupropion is an opioid antagonist, that designed!, high cholesterol, or other drugs you take drugs you take any medicines! Contrave group, a drug that blocks the effects of opioid drugs for use when diet and exercise have. Hormones, such as furosemide medications may cause some risk when taken together with our resources... Be the best analgesic choice risk for accidental overdose you stop using.... Trials, Contrave has shown better weight loss can increase the risk of certain side effects from beta-blockers with may.